Ensuring a healthy and successful pregnancy

What is PGT-SR?

PGT-SR, a reproductive genetic test, involves analyzing embryos from IVF to detect the presence or absence of an unbalanced form of structural rearrangement. Only embryos identified as normal or carriers of a balanced rearrangement, akin to the carrier parent, are selected and transferred to the uterus in the current or a subsequent IVF cycle.

Indicators of PGT-SR

Confirmed Structural Chromosome Rearrangement:

  • Couples with a confirmed structural chromosome rearrangement, increasing the risk of producing embryos with an incorrect chromosome complement.

Family History of Abnormal Karyotype:

  • Presence of a family history involving an abnormal karyotype and a confirmed balanced rearrangement (inversion, reciprocal translocation, or Robertsonian translocation) in one of the partners.

Previous Unbalanced Chromosomal Complement:

  • Couples who have experienced a previous pregnancy with an unbalanced chromosomal complement or have had an affected child

Benefits of PGT-SR

Embryo Assessment:

  • PGT-SR allows for the evaluation of embryos to identify those that are chromosomally normal and carriers of a balanced rearrangement where transferring them enables the selective transfer of only chromosomally normal embryos to the uterus.

Preventive Measure:

  • This approach acts as a preventive measure, aiming to avoid potential chromosomal irregularities that could lead to the development of genetic disorders in the fetus.

PGT-SR at Viafet

Viafet has extensive experience analyzing embryos for structural rearrangements. Our technology allows for the detection of SRs > 10 MB in size. Often, couples remain unaware to their carrier status for such rearrangements until post-IVF embryo testing. Viafet extends consultation services to these couples, substantiating the findings through Karyotype testing.

Ability to detect any SR >10Mb in size

Case to case consultation for every couple

Accurate and reliable diagnosis

Fast turn-around-time

Performed on Day 3 or Day 5 biopsy for fresh or frozen embryo transfer