Personalised Medicine

Personalised Medicine is a field of preventative genetics that urges individuals to preserve their health by learning about their genetic risk factors earlier in life.

Geneus™ is a genetic screening test that analyses changes, or variants, in your DNA. A Single Nucleotide Polymorphism (SNP) is a type of variant where a genetic sequence change is present at a specific position in our DNA. The change of a single nucleotide can either have no effect on the protein, or can alter protein structure/function that can lead to downstream changes. Although the majority of the SNPs are harmless, some have been shown to define our likelihood to develop specific traits, conditions, and diseases.

Through blood test, Geneus™ screens your DNA for the presence of 550 SNPs that are known to be associated with over 87 medical conditions. The presence of a SNP in your DNA will not change over the course of your life, making Geneus™ a once in a lifetime screening test.

For each condition or disease for which you carry an associated SNP, Geneus™ will provide you with your approximate risk percentile group; MyGeneus™ Risk.

What medical conditions are screened for with Geneus™?

How is MyGeneus™ risk calculated?

Geneus™ is the first personalized medicine genetic test to take into account all of the following important factors when calculating your genetic risk for each SNP which you carry:

1. Homozygous vs. Heterozygous Carrier Status:

Your predisposition to a certain disease or trait takes into account whether you inherited one copy (heterozygous) or two copies (homozygous) of the SNP from your parents.

2. Importance of Medical Risk Associated with the SNP:

Geneus™ considers SNPs that are associated with the trait or disease and, if possible, takes into account the odds ratio, the probability of developing the condition if you harbor a specific SNP.

3. Scientific Literature and Number of Associated Ethnicities:

Geneus™ considers the number of scientific reports a SNP has been documented in and the number of ethnicities it has been linked to.

The development of a specific trait or health condition is largely dependent on three factors:

• Genetic

• Environmental

• Lifestyle.

The genetic component contributes to a fraction of the risk, meaning the individual may have a genetic susceptibility to that trait or condition, but not destined to develop it. While we cannot change our genes, we can alter our lifestyle and environment to prevent or delay the condition.

MyGeneus™ Risk is classified in the following risk percentile categories:

Typical: Similar risk compared to an average person

Decreased: Protection from developing a trait, compared to the average person

Low: 1-33% increased risk, compared to the average person

Moderate: 34-67% increased risk, compared to the average person

Elevated: 68-100% increased risk, compared to the average person

Where can I get testing?

If you are interested in completing Personalized Medicine, contact Viafet and we will guide you on what to do next.

If at any time during your journey you have questions or would like to speak with a Genetic Counselor, contact Viafet and we will schedule an appointment immediately.